Susanna Ukonaho defended her PhD thesis ”Mandates and incentives: implementing Finlands first vaccination campaign against smallpox” at the University of Turku in June 2024.
Her opponent was prof. Romola Davenport (University of Cambridge, UK). Congratulations, Susanna!

View Susanna Ukonaho's doctoral dissertation here: https://urn.fi/URN:ISBN:978-951-29-9734-3

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Abstract

Vaccinations have succeeded in preventing many infectious diseases and the emergence and spread of epidemics. However, recently vaccination coverage has decreased especially in many high-income countries due to, among other things, growing reluctance to vaccinate. As a result, many infectious diseases such as measles and whooping cough are on the rise. To prevent the effects of declining vaccine uptake, there is a global search for functional strategies to increase vaccination coverage.

Finlands first vaccination campaign against smallpox started in 1802, only a few years after the development of the first vaccine. Smallpox was eventually eliminated from Finland in 1941, but little is known about how this vaccination campaign was implemented, and to what extent it was successful. This thesis investigated the implementation of Finland’s first vaccination campaign against smallpox through three key factors: vaccination mandates, socio-economic status, and the family network.

The thesis found that Finland’s mandatory vaccination law was successful in improving vaccination coverage, surpassing 80% coverage required for herd immunity against smallpox. However, the law had varied impact on the socio-economic groups. In particular, for the lowest socio-economic group, the change in vaccination coverage was minimal and remained far behind that of other groups, highlighting the need for additional interventions to increase vaccine uptake in low-coverage communities. Grandmothers improved child survival from many infectious diseases, including smallpox, but had no effect on vaccine uptake. Hence public health authorities should find alternative strategies to promote vaccination.

These findings enable public health workers to make informed decisions on the strategies to combat declining vaccination coverage and offers general conclusions applicable to contemporary vaccination campaigns.

Other News

We are delighted to once again host PhD candidate Silke van Daalen, who will stay with us for most of September.

Laisk T, Tšuiko O, Jatsenko T, Hõrak P, Otala M, Lahdenperä M, Lummaa V, Tuuri T, Salumets A, Tapanainen JS:

Simon's latest work on the demography of grandmothers is now out in PLoS ONE. 

We were delighted to host Professors Martin Daly and Gretchen Perry for a day of excellent talks, with a particular focus on grandmothering and alloparental behaviour.

Robert Lynch is at the Human Behavior and Evolution Society (HBES) conference 2018 in Amsterdam

The manuscript "The transition to modernity and chronic disease: mismatch and natural selection" by Stephen Corbett, Alexandre Courtiol, Virpi Lummaa, Jacob Moorad and Stephen Stea

Two papers out now from Simon's PhD project!

1) Changes in the Length of Grandparenthood in Finland 1790-1959, published in the Finnish Yearbook of Population Reasarch. In this paper, the team investigated how the shared time between grandparents and grandchildren changed across the demographic transition and with industrialisation. This shared time was low and stable before these major events, and began to increase rapidly after they began.

2) Limited support for the X-linked grandmother hypothesis in pre-industrial Finland, published in Biology Letters. Here, we tested whether slight differences in relatedness via the X-chromosome might lead to differences the survival of male and female grandchildren with maternal or paternal grandmothers. Though two of three predictions were supported, we concluded that the X-linked grandmother hypothesis cannot account for lineage differences by itself. 

Our latest paper shows that early-life environment is associated with sex differences in adult mortality and expected lifespan. Out now in Ecology Letters:
http://doi.wiley.com/10.1111/ele.12888

Figure 3a+b, from Griffin et al. 2017

Our review of the contribution of human studies to evolutionary biology is out now in Proceedings of the Royal Society B:
http://rspb.royalsocietypublishing.org/content/284/1866/20171164